GATA2 mutations and overexpression in pediatric acute myeloid leukemia

• Main Authors: Zhenzhen Yang (Author), Xingjuan Wang (Author), Xi Chen (Author), Hu Dou (Author), Yi Huang (Author), Ling Lu (Author), Lin Zou (Author), Junqin Bi (Author), Meng Su (Author), Jie Yu (Author), Liming Bao (Author)
• Format: Book
• Published: Elsevier, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: GATA2 is important for the regulation of development and proliferation of early pluripotent hematopoietic precursors, and precise GATA2 expression is critical in myeloid lineage maturation. GATA2 mutations have been reported in acute myeloid leukemia (AML) but only few studies of GATA2 m...