Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

• 主要な著者: Peter Seiron (著者), Anna Wiberg (著者), Enida Kuric (著者), Lars Krogvold (著者), Frode L Jahnsen (著者), Knut Dahl‐Jørgensen (著者), Oskar Skog (著者), Olle Korsgren (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2019-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) wou...