Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

• Asıl Yazarlar: Peter Seiron (Yazar), Anna Wiberg (Yazar), Enida Kuric (Yazar), Lars Krogvold (Yazar), Frode L Jahnsen (Yazar), Knut Dahl‐Jørgensen (Yazar), Oskar Skog (Yazar), Olle Korsgren (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2019-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) wou...