Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups

• Asıl Yazarlar: Qi Wang (Yazar), Jie Liu (Yazar), Zi-Dan Zhou (Yazar), Ke-Xin Zhou (Yazar), Fei Li (Yazar), Qi-Wen Zhang (Yazar), Shou-Kai Wang (Yazar), Wei Wang (Yazar), Zhen Jin (Yazar), You-Zhi Tang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A series of pleuromutilin derivatives containing alkylamine and nitrogen heterocycle groups were designed and synthesised under mild conditions. The in vitro antibacterial activity of these semisynthetic derivatives against four strains of Staphylococcus aureus (MRSA ATCC 43300, S.aureus ATCC 29213,...