Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses

• Autori principali: Elizaveta S. Darnotuk (Autore), Andrei E. Siniavin (Autore), Natal'ya S. Shastina (Autore), Sergey I. Luyksaar (Autore), Anna M. Inshakova (Autore), Natalia E. Bondareva (Autore), Sergey A. Zolotov (Autore), Nadezhda L. Lubenec (Autore), Anna B. Sheremet (Autore), Denis Y. Logunov (Autore), Nailya A. Zigangirova (Autore), Vladimir A. Gushchin (Autore), Alexander L. Gintsburg (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The spread of COVID-19 infection continues due to the emergence of multiple transmissible and immune-evasive variants of the SARS-CoV-2 virus. Although various vaccines have been developed and several drugs have been approved for the treatment of COVID-19, the development of new drugs to combat COVI...