Single cell RNA sequencing provides novel cellular transcriptional profiles and underlying pathogenesis of presbycusis

• Main Authors: Juhong Zhang (Author), Lili Xiang (Author), Wenfang Sun (Author), Menglong Feng (Author), Zhiji Chen (Author), Hailan Mo (Author), Haizhu Ma (Author), Li Yang (Author), Shaojing Kuang (Author), Yaqin Hu (Author), Jialin Guo (Author), Yijun Li (Author), Wei Yuan (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Age-related hearing loss (ARHL) or presbycusis is associated with irreversible progressive damage in the inner ear, where the sound is transduced into electrical signal; but the detailed mechanism remains unclear. Here, we sought to determine the potential molecular mechanism involved in th...