Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein-Barr virus infection and high‐ and low‐microsatellite instability

• Main Authors: Meike Kohlruss (Author), Bianca Grosser (Author), Marie Krenauer (Author), Julia Slotta‐Huspenina (Author), Moritz Jesinghaus (Author), Susanne Blank (Author), Alexander Novotny (Author), Magdalena Reiche (Author), Thomas Schmidt (Author), Liridona Ismani (Author), Alexander Hapfelmeier (Author), Daniel Mathias (Author), Petra Meyer (Author), Matthias M Gaida (Author), Lukas Bauer (Author), Katja Ott (Author), Wilko Weichert (Author), Gisela Keller (Author)
• Format: Book
• Published: Wiley, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Epstein-Barr virus positivity (EBV(+)) and high‐microsatellite instability (MSI‐H) have been identified as molecular subgroups in gastric carcinoma. The aim of our study was to determine the prognostic and predictive relevance of these subgroups in the context of platinum/5‐fluorouracil (5‐...