Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records

• मुख्य लेखकों: Katherine S. Ruth (लेखक), Robin N. Beaumont (लेखक), Jonathan M. Locke (लेखक), Jessica Tyrrell (लेखक), Carolyn J. Crandall (लेखक), Gareth Hawkes (लेखक), Timothy M. Frayling (लेखक), Julia K. Prague (लेखक), Kashyap A. Patel (लेखक), Andrew R. Wood (लेखक), Michael N. Weedon (लेखक), Anna Murray (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2023-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Vasomotor symptoms (VMS) can often significantly impact women's quality of life at menopause. In vivo studies have shown that increased neurokinin B (NKB) / neurokinin 3 receptor (NK3R) signalling contributes to VMS, with previous genetic studies implicating the TACR3 gene l...