Antiplatelet Effect of NQ12: a Possible Mechanism Through the Arachidonic Acid Cascade

• Main Authors: Yong-Ri Jin (Author), Xiang-Hua Han (Author), Jung-Jin Lee (Author), Yong Lim (Author), Tack-Joong Kim (Author), Hwan-Soo Yoo (Author), Jin-Tae Hong (Author), Chong-Kil Lee (Author), Yeo-Pyo Yun (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

NQ12, an antithrombotic agent, has been reported to display a potent antiplatelet activity. This study was undertaken to reveal the effect of NQ12 on rabbit platelet aggregation and signal transduction involved in the arachidonic acid (AA) cascade. NQ12 concentration-dependently suppressed collagen-...