Direct detection of drug-resistant Mycobacterium tuberculosis using targeted next generation sequencing

• Main Authors: Shannon G. Murphy (Author), Carol Smith (Author), Pascal Lapierre (Author), Joseph Shea (Author), Kruthikaben Patel (Author), Tanya A. Halse (Author), Michelle Dickinson (Author), Vincent Escuyer (Author), Marie Claire Rowlinson (Author), Kimberlee A. Musser (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis complex (MTBC) infections are treated with combinations of antibiotics; however, these regimens are not as efficacious against multidrug and extensively drug resistant MTBC. Phenotypic (growth-based) drug susceptibility testing on slow growing bacteria like MTBC requires m...