Monoclonal antibody therapy efficacy can be boosted by combinations with other treatments: Predictions using an integrated Alzheimer's Disease Platform

• Main Authors: Tatiana Karelina (Author), Stepan Lerner (Author), Alexandr Stepanov (Author), Mark Meerson (Author), Oleg Demin (Author)
• Format: Bog
• Udgivet: Wiley, 2021-06-01T00:00:00Z.
• Fag: article
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Abstract For many years, clinical research in Alzheimer's disease (AD) has focused on attempts to identify the most explicit biomarker, namely amyloid beta. Unfortunately, the numerous therapies that have been developed have failed in clinical practice. AD arises as a consequence of multiple fa...