Prophylactic and Ameliorative Effects of PPAR-γ Agonist Pioglitazone in Improving Oxidative Stress, Germ Cell Apoptosis and Inflammation in Gentamycin-Induced Testicular Damage in Adult Male Albino Rats

• Egile Nagusiak: Karima El-Sayed (Egilea), Dina A. Ali (Egilea), Shymaa Ahmed Maher (Egilea), Dalia Ghareeb (Egilea), Samy Selim (Egilea), Sarah Albogami (Egilea), Eman Fayad (Egilea), Eman Kolieb (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Peroxisome proliferator-activated receptor gamma (PPAR-γ) is ubiquitously expressed in testicular tissue and plays a crucial role in regulating various physiological processes. Pioglitazone (PIO) is one of the PPAR-γ agonists, having anti-oxidant and anti-inflammatory effects. Patients on gentamycin...