Organic Anion Transporting Polypeptides 1B1 and 1B3 Play an Important Role in Uremic Toxin Handling and Drug-Uremic Toxin Interactions in the Liver

PURPOSE. Organic anion-transporting polypeptide (OATP) 1B1 and OATP1B3 contribute to hepatic uptake of numerous drugs. Thus, reduced OATP1B1 and OATP1B3 activity in chronic kidney disease (CKD) may have a major impact on the hepatic clearance of drugs. The effect of drug-uremic toxin interactions on...

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Main Authors: Toshihiro Sato (Author), Hiroaki Yamaguchi (Author), Takuma Kogawa (Author), Takaaki Abe (Author), Nariyasu Mano (Author)
Format: Book
Published: Frontiers Media S.A., 2014-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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