Reprogramming the Dynamin 2 mRNA by Spliceosome-mediated RNA Trans-splicing

• Principais autores: Delphine Trochet (Autor), Bernard Prudhon (Autor), Arnaud Jollet (Autor), Stéphanie Lorain (Autor), Marc Bitoun (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Dynamin 2 (DNM2) is a large GTPase, ubiquitously expressed, involved in membrane trafficking and regulation of actin and microtubule cytoskeletons. DNM2 mutations cause autosomal dominant centronuclear myopathy which is a rare congenital myopathy characterized by skeletal muscle weakness and histopa...