Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum

• मुख्य लेखकों: Simone Giovannuzzi (लेखक), Viviana De Luca (लेखक), Alessio Nocentini (लेखक), Clemente Capasso (लेखक), Claudiu T. Supuran (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Coumarins were discovered to act as inhibitors of α-carbonic anhydrases (CAs, EC 4.2.1.1) after undergoing hydrolysis mediated by the esterase activity of the enzyme to the corresponding 2-hydroxycinnamic acids. Other classes of CAs among the eight currently known do not possess esterase activity or...