Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance

• Main Authors: Rosanne M. Smits (Author), Dieuwke S. Veldhuijzen (Author), Henriet van Middendorp (Author), Petra C. E. Hissink Muller (Author), Wineke Armbrust (Author), Elizabeth Legger (Author), Nico M. Wulffraat (Author), Andrea W. M. Evers (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Methotrexate (MTX) therapy has proven to be a successful and safe treatment for Juvenile Idiopathic Arthritis (JIA). Despite the high efficacy rates of MTX, treatment outcomes are often complicated by burdensome gastro-intestinal side effects. Intolerance rates for MTX in childre...