Root canal contamination or exposure to lipopolysaccharide differentially modulate prostaglandin E 2 and leukotriene B 4 signaling in apical periodontitis

• Main Authors: Francisco Wanderley Garcia PAULA-SILVA (Author), Fernanda Regina RIBEIRO-SANTOS (Author), Igor Bassi Ferreira PETEAN (Author), Maya Fernanda MANFRIN ARNEZ (Author), Luciano Aparecido de ALMEIDA-JUNIOR (Author), Fabrício Kitazono de CARVALHO (Author), Léa Assed Bezerra da SILVA (Author), Lúcia Helena FACCIOLI (Author)
• Format: Book
• Published: University of São Paulo, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose To evaluate the kinetics of apical periodontitis development in vivo , induced either by contamination of the root canals by microorganisms from the oral cavity or by inoculation of bacterial lipopolysaccharide (LPS) and the regulation of major enzymes and receptors involved in the...