Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model

Human epidermal growth factor receptor 3 (HER3) has been increasingly scrutinized as a potential drug target since the elucidation of its role in mediating tumor growth and acquired therapy resistance. Affibody molecules are so-called scaffold proteins with favorable biophysical properties, such as...

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Main Authors: Charles Dahlsson Leitao (Author), Sara S. Rinne (Author), Mohamed Altai (Author), Olga Vorontsova (Author), Finn Dunås (Author), Per Jonasson (Author), Vladimir Tolmachev (Author), John Löfblom (Author), Stefan Ståhl (Author), Anna Orlova (Author)
Format: Book
Published: MDPI AG, 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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