Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma

• প্রধান লেখক: Jing Lin (লেখক), Jia Hui Jane Lee (লেখক), Kathirvel Paramasivam (লেখক), Elina Pathak (লেখক), Zhenxun Wang (লেখক), Zacharias Aloysius Dwi Pramono (লেখক), Bing Lim (লেখক), Keng Boon Wee (লেখক), Uttam Surana (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2017-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Self-renewing tumor-initiating cells (TICs) are thought to be responsible for tumor recurrence and chemo-resistance. Glycine decarboxylase, encoded by the GLDC gene, is reported to be overexpressed in TIC-enriched primary non-small-cell lung carcinoma (NSCLC). GLDC is a component of the mitochondria...