Hydroxychloroquine induces apoptosis of myeloid-derived suppressor cells via up-regulation of CD81 contributing to alleviate lupus symptoms

• Hoofdauteurs: Jiali Ni (Auteur), Haiyan Zhu (Auteur), Li Lu (Auteur), Zihe Zhao (Auteur), Jiaxuan Jiang (Auteur), Xiaokang You (Auteur), Yuzhu Wang (Auteur), Yuliang Ma (Auteur), Zirui Yang (Auteur), Yayi Hou (Auteur), Huan Dou (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2022-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that results from widespread immune complex deposition and secondary tissue injury. Hydroxychloroquine (HCQ) has been used clinically to treat SLE, while its exact mechanism has still remained elusive. Some studi...