Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood

• Main Authors: Alejandro Rodríguez‐Pena (Author), Estibaliz Armendariz (Author), Alvaro Oyarbide (Author), Xabier Morales (Author), Sergio Ortiz‐Espinosa (Author), Borja Ruiz‐Fernández de Córdoba (Author), Denis Cochonneau (Author), Iñaki Cornago (Author), Dominique Heymann (Author), Josepmaría Argemi (Author), Delia D'Avola (Author), Bruno Sangro (Author), Fernando Lecanda (Author), Ruben Pio (Author), Iván Cortés‐Domínguez (Author), Carlos Ortiz‐de‐Solórzano (Author)
• Format: Book
• Published: Wiley, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The analysis of circulating tumor cells (CTCs) in blood is a powerful noninvasive alternative to conventional tumor biopsy. Inertial‐based separation is a promising high‐throughput, marker‐free sorting strategy for the enrichment and isolation of CTCs. Here, we present and validate a double...