Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

• Asıl Yazarlar: Mona F. Said (Yazar), Riham F. George (Yazar), Andrea Petreni (Yazar), Claudiu T. Supuran (Yazar), Nada M. Mohamed (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In continuation of our previous studies to optimise potent carbonic anhydrase inhibitors, two new series of isatin N-phenylacetamide based sulphonamides were synthesised and screened for their human (h) carbonic anhydrase (EC 4.2.1.1) inhibitory activities against four isoforms hCA I, hCA II, hCA IX...