Proteomic profiling of the brain from the <i>wobbler</i> mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein

• मुख्य लेखकों: Sandra Murphy (लेखक), Thomas Schmitt-John (लेखक), Paul Dowling (लेखक), Michael Henry (लेखक), Paula Meleady (लेखक), Dieter Swandulla (लेखक), Kay Ohlendieck (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: PAGEPress Publications, 2023-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The wobbler mouse is a widely used model system of amyotrophic lateral sclerosis and exhibits progressive neurodegeneration and neuroinflammation in association with skeletal muscle wasting. This study has used wobbler brain preparations for the systematic and mass spectrometric determination of pro...