A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption

• Main Authors: Hyun-moon Back (Author), Byungjeong Song (Author), Sudeep Pradhan (Author), Jung-woo Chae (Author), Nayoung Han (Author), Wonku Kang (Author), Min Jung Chang (Author), Jiao Zheng (Author), Kwang-il Kwon (Author), Mats O. Karlsson (Author), Hwi-yeol Yun (Author)
• Formato: Livro
• Publicado em: BMC, 2018-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Oral administration of drugs is convenient and shows good compliance but it can be affected by many factors in the gastrointestinal (GI) system. Consumption of food is one of the major factors affecting the GI system and consequently the absorption of drugs. The aim of this study...