Sirtuin inhibition and neurite outgrowth effect as new biological activities for Areca catechu nut alkaloids

• Main Authors: Yoshiyuki Hirata (Author), Hinata Nishino (Author), Tsutomu Sasaki (Author), Yasuo Nagaoka (Author), Shinichi Uesato (Author), Masahiko Taniguchi (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Areca catechu is distributed in Southeast Asia, and its nut is called "Binrouji" in Japanese. A. nut contains alkaloids typified by arecoline (1), which are reported to exhibit nicotine-like activities such as parasympathetic nerve excitatory activity. A. nut alkaloids, 1, arec...