Unveiling the dark side of glucose-regulated protein 78 (GRP78) in cancers and other human pathology: a systematic review

• Main Authors: Amos Olalekan Akinyemi (Author), Kendall Elizabeth Simpson (Author), Sunday Faith Oyelere (Author), Maria Nur (Author), Chrispus Mutuku Ngule (Author), Bolaji Charles Dayo Owoyemi (Author), Vivian Adiila Ayarick (Author), Felix Femi Oyelami (Author), Oluwafunminiyi Obaleye (Author), Dave-Preston Esoe (Author), Xiaoqi Liu (Author), Zhiguo Li (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Glucose-Regulated Protein 78 (GRP78) is a chaperone protein that is predominantly expressed in the lumen of the endoplasmic reticulum. GRP78 plays a crucial role in protein folding by assisting in the assembly of misfolded proteins. Under cellular stress conditions, GRP78 can translocate to...