Model-based optimization of the primary drying phase of oral lyophilizates

• Những tác giả chính: Brecht Vanbillemont (Tác giả), Thomas De Beer (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2020-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Oral lyophilizates also called orally disintegrating tablets (ODTs) are a patient friendly and convenient dosage form. They are manufactured by dosing a suspension in blister cups and subsequently freeze-drying these blisters to achieve porous tablets that disintegrate quickly (< 10 s) when place...