Triple oral beta-lactam containing therapy for Buruli ulcer treatment shortening.

• Main Authors: María Pilar Arenaz-Callao (Author), Rubén González Del Río (Author), Ainhoa Lucía Quintana (Author), Charles J Thompson (Author), Alfonso Mendoza-Losana (Author), Santiago Ramón-García (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The potential use of clinically approved beta-lactams for Buruli ulcer (BU) treatment was investigated with representative classes analyzed in vitro for activity against Mycobacterium ulcerans. Beta-lactams tested were effective alone and displayed a strong synergistic profile in combination with an...