Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

• मुख्य लेखकों: Luca F. Roggeveen (लेखक), Tingjie Guo (लेखक), Ronald H. Driessen (लेखक), Lucas M. Fleuren (लेखक), Patrick Thoral (लेखक), Peter H. J. van der Voort (लेखक), Armand R. J. Girbes (लेखक), Rob J. Bosman (लेखक), Paul Elbers (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

IntroductionAntibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but requi...