Preclinical evaluation of ELP‐004 in mice

• Main Authors: Jamie L. McCall (Author), Werner J. Geldenhuys (Author), Lisa J. Robinson (Author), Michelle R. Witt (Author), Peter M. Gannett (Author), Björn C. G. Söderberg (Author), Harry C. Blair (Author), Jonathan Soboloff (Author), John B. Barnett (Author)
• Formato: Livro
• Publicado em: Wiley, 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract This study provides a detailed understanding of the preclinical pharmacokinetics and metabolism of ELP‐004, an osteoclast inhibitor in development for the treatment of bone erosion. Current treatments for arthritis, including biological disease‐modifying antirheumatic drugs, are not well‐to...