Proteomic analysis and experimental validation reveal the blood-brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer's disease

• Main Authors: Yunfang Su (Author), Ningning Liu (Author), Pan Wang (Author), Congcong Shang (Author), Ruiqin Sun (Author), Jinlian Ma (Author), Zhonghua Li (Author), Huifen Ma (Author), Yiran Sun (Author), Zijuan Zhang (Author), Junying Song (Author), Zhishen Xie (Author), Jiangyan Xu (Author), Zhenqiang Zhang (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Huanshaodan (HSD) is a Chinese Herbal Compound which has a definite clinical effect on Alzheimer's disease (AD), however, the underlying mechanism remains unclear. The aim of this study is to preliminarily reveal the mechanism of HSD in the treatment of AD model of SAMP8 mic...