Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis

• Main Authors: Lang Yi (Author), Mingju Hao (Author), Tian Lu (Author), Guigao Lin (Author), Lida Chen (Author), Ming Gao (Author), Gaowei Fan (Author), Dong Zhang (Author), Guojing Wang (Author), Xin Yang (Author), Yulong Li (Author), Kuo Zhang (Author), Rui Zhang (Author), Yanxi Han (Author), Lunan Wang (Author), Jinming Li (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a challenge. Here, we developed a double-sandwich enzyme-li...