Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis

• Главные авторы: Lang Yi (Автор), Mingju Hao (Автор), Tian Lu (Автор), Guigao Lin (Автор), Lida Chen (Автор), Ming Gao (Автор), Gaowei Fan (Автор), Dong Zhang (Автор), Guojing Wang (Автор), Xin Yang (Автор), Yulong Li (Автор), Kuo Zhang (Автор), Rui Zhang (Автор), Yanxi Han (Автор), Lunan Wang (Автор), Jinming Li (Автор)
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• Опубликовано: Hindawi Limited, 2016-01-01T00:00:00Z.
• Предметы: article
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The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a challenge. Here, we developed a double-sandwich enzyme-li...