Juvenile Idiopathic Arthritis Subtype- and Sex-specific Associations with Genetic Variants in the PSMA6/PSMC6/PSMA3 Gene Cluster

• Main Authors: Tatjana Sjakste (Author), Natalia Paramonova (Author), Ingrida Rumba-Rozenfelde (Author), Ilva Trapina (Author), Olga Sugoka (Author), Nikolajs Sjakste (Author)
• Format: Book
• Published: Elsevier, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ubiquitin proteasome system plays an exceptional biological role in the antigen processing and immune response and it could potentially be involved in pathogenesis of many immunity-related diseases, including juvenile idiopathic arthritis (JIA). Methods: The PSMB5 (rs11543947), PSMA6 (rs2277460,...