HIV drug resistance in sub-Saharan Africa: public health questions and the potential role of real-world data and mathematical modelling

• Main Authors: Reneé de Waal (Author), Richard Lessells (Author), Anthony Hauser (Author), Roger Kouyos (Author), Mary-Ann Davies (Author), Matthias Egger (Author), Gilles Wandeler (Author)
• Format: Book
• Published: Elsevier, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The prevalence of pretreatment resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is >10% in many low-income countries. As a consequence, several sub-Saharan African countries have implemented, or are considering the introduction of, non-NNRTI-based first-line antiretroviral t...