Involvement of the Long-Chain Fatty Acid Receptor GPR40 in Depression-Related Behavior

• Main Authors: Takashi Nishinaka (Author), Takuya Yamashita (Author), Kazuo Nakamoto (Author), Fumiyo Kasuya (Author), Shogo Tokuyama (Author)
• Formato: Livro
• Publicado em: Elsevier, 2014-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract.: The functional role of brain G protein-coupled receptor 40 (GPR40) remains unclear. We investigated GPR40 signaling in depression-related behavior in mice via the forced swim test. A repeated but not a single intracerebroventricular administration of the GPR40 agonist, GW9508, reduced the...