Acetylcholine receptor-β inhibition by interleukin-6 in skeletal muscles contributes to modulating neuromuscular junction during aging

• Main Authors: Yanling Zhao (Author), Han Yan (Author), Ke Liu (Author), Jiangping Ma (Author), Wenlan Sun (Author), Hejin Lai (Author), Hongli Li (Author), Jianbang Gu (Author), He Huang (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aging-related strength decline contributes to physiological deterioration and is a good predictor of poor prognosis. However, the mechanisms underlying neuromuscular junction disorders affecting contraction in aging are not well described. We hypothesized that the autocrine effec...