The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer

• 主要な著者: Mueller Christopher R (著者), McCoy Marcia L (著者), Roskelley Calvin D (著者)
• フォーマット: 図書
• 出版事項: BMC, 2003-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Mutations within the BRCA1 tumor suppressor gene occur frequently in familial epithelial ovarian carcinomas but they are a rare event in the much more prevalent sporadic form of the disease. However, decreased BRCA1 expression occurs frequently in sporadic tumors...