Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)

• Main Authors: Kelsey A. Carpenter (Author), Delia O. Alkhatib (Author), Bryan A. Dulion (Author), Elizabeth Guirado (Author), Shreya Patel (Author), Yinghua Chen (Author), Anne George (Author), Ryan D. Ross (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract X-linked hypophosphatemia (XLH) is a rare disease of elevated fibroblast growth factor 23 (FGF23) production that leads to hypophosphatemia and impaired mineralization of bone and teeth. The clinical manifestations of XLH include a high prevalence of dental abscesses and periodontal disease...