Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body

• Main Authors: Maximilian Hammer (Author), Sonja K. Schickhardt (Author), Patrick R. Merz (Author), Ramin Khoramnia (Author), Alexander F. Scheuerle (Author), Walter Mier (Author), Philipp Uhl (Author), Gerd U. Auffarth (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Silicone oil endotamponades provide a reservoir for drugs in the eye. Following vitrectomy surgery to treat retinal detachments, extensive diabetic retinopathy or endophthalmitis, they can be used as long-term lipophilic depots. This study aimed to investigate the physicochemical properties of intra...