Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

• Main Authors: Kimball Scot R (Author), Brucklacher Robert M (Author), VanGuilder Heather D (Author), Bixler Georgina V (Author), Bronson Sarah K (Author), Freeman Willard M (Author)
• Format: Book
• Published: BMC, 2011-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. Approximately 95% of patients with Type 1 diabetes develop some degree of retinopathy within 25 years of diagnosis despite normalization of blood glucos...