Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

• Главные авторы: Kimball Scot R (Автор), Brucklacher Robert M (Автор), VanGuilder Heather D (Автор), Bixler Georgina V (Автор), Bronson Sarah K (Автор), Freeman Willard M (Автор)
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• Опубликовано: BMC, 2011-05-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. Approximately 95% of patients with Type 1 diabetes develop some degree of retinopathy within 25 years of diagnosis despite normalization of blood glucos...