Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A

• Main Authors: Songmao Zheng (Author), Fang Shen (Author), Brian Jones (Author), Damien Fink (Author), Brian Geist (Author), Ivo Nnane (Author), Zhao Zhou (Author), Jeff Hall (Author), Ravi Malaviya (Author), Tatiana Ort (Author), Weirong Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor necrosis factor (TNF) and interleukin (IL)-17A are pleiotropic cytokines implicated in the pathogenesis of several autoimmune diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA). JNJ-61178104 is a novel human anti-TNF and anti-IL-17A monovalent, bispecific antibody that...