CD44v6+ Hepatocellular Carcinoma Cells Maintain Stemness Properties through Met/cJun/Nanog Signaling

• Main Authors: Wei Chen (Author), Ronghua Wang (Author), Yuchong Zhao (Author), Yawen Li (Author), Xiju Wang (Author), Wang Peng (Author), Shuya Bai (Author), Mengli Zheng (Author), Man Liu (Author), Bin Cheng (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer stem cells (CSCs) are characterized by their self-renewal and differentiation abilities. CD44v6 is a novel CSC marker that can activate various signaling pathways. Here, we hypothesized that the HGF/Met signaling pathway promotes stemness properties in CD44v6+ hepatocellular carcinoma (HCC) c...