Simultaneous Quantitation of a Novel α1/β1-Blocker TJ0711 and Its Two Metabolites in Dog Plasma Using LC-MS/MS and Its Application to a Pharmacokinetic Study after Intravenous Infusion

TJ0711∙HCl, which is a novel α1/β1 adrenoceptor blocking agent with a ratio of 1:1 for α1/β1, is designed to treat and prevent perioperative hypertension. M1 and M3 were identified as important metabolites in vitro for either antihypertension activity or the maj...

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ग्रंथसूची विवरण
मुख्य लेखकों: Wenwen Zhu (लेखक), Wanyu Liu (लेखक), Haojv Li (लेखक), Guojia Xu (लेखक), Qian Li (लेखक), Jiangeng Huang (लेखक), Gao Li (लेखक), Luqin Si (लेखक)
स्वरूप: पुस्तक
प्रकाशित: MDPI AG, 2019-01-01T00:00:00Z.
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