Simultaneous Quantitation of a Novel α1/β1-Blocker TJ0711 and Its Two Metabolites in Dog Plasma Using LC-MS/MS and Its Application to a Pharmacokinetic Study after Intravenous Infusion
TJ0711∙HCl, which is a novel α1/β1 adrenoceptor blocking agent with a ratio of 1:1 for α1/β1, is designed to treat and prevent perioperative hypertension. M1 and M3 were identified as important metabolites in vitro for either antihypertension activity or the maj...
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मुख्य लेखकों: | , , , , , , , |
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स्वरूप: | पुस्तक |
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MDPI AG,
2019-01-01T00:00:00Z.
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A1234.567 |
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प्रति 1 | उपलब्ध |