Phosphatidylinositol-3 kinase-Akt-mammalian target of rapamycin signaling pathway mediates contractility of human endometriotic stromal cells: A promising new target for the treatment of endometriosis-associated fibrosis

Objective: To assess the involvement of phosphatidylinositol-3 kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) on the extracellular matrix contractility of endometriotic cells. Materials and methods: The effects of wortmannin, LY294002, Akt inhibitor IV, and Ku-0063794 on the contractility of...

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Main Authors: Wakana Abe (Author), Kaei Nasu (Author), Akitoshi Tsuno (Author), Yukie Kawano (Author), Hisashi Narahara (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-11-01T00:00:00Z.
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