HER3 signaling and targeted therapy in cancer

• Ngā kaituhi matua: Rosalin Mishra (Author), Hima Patel (Author), Samar Alanazi (Author), Long Yuan (Author), Joan T. Garrett (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

ERBB family members including epidermal growth factor receptor (EGFR) also known as HER1, ERBB2/HER2/Neu, ERBB3/HER3 and ERBB4/HER4 are aberrantly activated in multiple cancers and hence serve as drug targets and biomarkers in modern precision therapy. The therapeutic potential of HER3 has long been...