Relationship between drug targets and drug-signature networks: a network-based genome-wide landscape

• Main Authors: Chae Won Lee (Author), Sung Min Kim (Author), Soonok Sa (Author), Myunghee Hong (Author), Sang-Min Nam (Author), Hyun Wook Han (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Drugs produce pharmaceutical and adverse effects that arise from the complex relationship between drug targets and signatures; by considering such relationships, we can begin to understand the cellular mechanisms of drugs. In this study, we selected 463 genes from the DSigDB database corres...