Oxalate-induced apoptosis through ERS-ROS-NF-κB signalling pathway in renal tubular epithelial cell

• Автори: Shaoxiong Ming (Автор), Jia Tian (Автор), Ke Ma (Автор), Chengbin Pei (Автор), Ling Li (Автор), Zeyu Wang (Автор), Ziyu Fang (Автор), Min Liu (Автор), Hao Dong (Автор), Weijian Li (Автор), Jianwen Zeng (Автор), Yonghan Peng (Автор), Xiaofeng Gao (Автор)
• Формат: Книга
• Опубліковано: BMC, 2022-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Kidney stones are composed of approximately 70-80% calcium oxalate. However, the exact mechanism of formation of calcium oxalate kidney stones remains unclear. In this study, we investigated the roles of endoplasmic reticulum stress (ERS), reactive oxygen species (ROS), and the N...