Oxalate-induced apoptosis through ERS-ROS-NF-κB signalling pathway in renal tubular epithelial cell

• Main Authors: Shaoxiong Ming (Author), Jia Tian (Author), Ke Ma (Author), Chengbin Pei (Author), Ling Li (Author), Zeyu Wang (Author), Ziyu Fang (Author), Min Liu (Author), Hao Dong (Author), Weijian Li (Author), Jianwen Zeng (Author), Yonghan Peng (Author), Xiaofeng Gao (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Kidney stones are composed of approximately 70-80% calcium oxalate. However, the exact mechanism of formation of calcium oxalate kidney stones remains unclear. In this study, we investigated the roles of endoplasmic reticulum stress (ERS), reactive oxygen species (ROS), and the N...