Calycosin Alleviates Sepsis-Induced Acute Lung Injury via the Inhibition of Mitochondrial ROS-Mediated Inflammasome Activation

• Main Authors: Yu Xia (Author), Yuanbao Cao (Author), Yao Sun (Author), Xiuying Hong (Author), Yingyan Tang (Author), Juan Yu (Author), Hongjuan Hu (Author), Wenjia Ma (Author), Kailun Qin (Author), Rui Bao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis-induced acute lung injury (ALI) culminates in multiple organ failure via uncontrolled inflammatory responses and requires effective treatment. Herein, we aimed to investigate the effect of calycosin (CA), a natural isoflavonoid, on sepsis-induced ALI. CA attenuated lipopolysaccharide (LPS) an...