Involvement of Adenosine A2a Receptor in Intraocular Pressure Decrease Induced by 2-(1-Octyn-1-yl)adenosine or 2-(6-Cyano-1-hexyn-1-yl)adenosine

• Asıl Yazarlar: Takashi Konno (Yazar), Akira Murakami (Yazar), Takehiro Uchibori (Yazar), Akihiko Nagai (Yazar), Kentaro Kogi (Yazar), Norimichi Nakahata (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2005-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The aim of the present study is to clarify the mechanism for the decrease in intraocular pressure by 2-alkynyladenosine derivatives in rabbits. The receptor binding analysis revealed that 2-(1-octyn-1-yl)adenosine (2-O-Ado) and 2-(6-cyano-1-hexyn-1-yl)adenosine (2-CN-Ado) selectively bound to the A2...