Functional Duality of Chondrocyte Hypertrophy and Biomedical Application Trends in Osteoarthritis

• Main Authors: Sunghyun Park (Author), Alvin Bello (Author), Yoshie Arai (Author), Jinsung Ahn (Author), Dohyun Kim (Author), Kyung-Yup Cha (Author), Inho Baek (Author), Hansoo Park (Author), Soo-Hong Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chondrocyte hypertrophy is one of the key indicators in the progression of osteoarthritis (OA). However, compared with other OA indications, such as cartilage collapse, sclerosis, inflammation, and protease activation, the mechanisms by which chondrocyte hypertrophy contributes to OA remain elusive....