Physiological and pathophysiological insights of Nav1.4 and Nav1.5 comparison

• Main Authors: Gildas eLoussouarn (Author), Damien eSternberg (Author), Sophie eNicole (Author), Céline eMarionneau (Author), Françoise eLe Bouffant (Author), Gilles eToumaniantz (Author), Julien eBarc (Author), Olfat eMalak (Author), Véronique eFressart (Author), Yann ePéréon (Author), Isabelle eBaró (Author), Flavien eCharpentier (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mutations in Nav1.4 and Nav1.5 α-subunits have been associated with muscular and cardiac channelopathies, respectively. Despite intense research on the structure and function of these channels, a lot of information is still missing to delineate the various physiological and pathophysiological proces...